Dr Indrajit Lahiri

School of Biosciences

Lecturer in Electron Microscopy

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i.lahiri@sheffield.ac.uk
+44 114 222 20035

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Dr Indrajit Lahiri
School of Biosciences
D14A
Firth Court
Western Bank
91Ö±²¥
S10 2TN
Profile

2022 - present: Lecturer in Electron Microscopy, University of 91Ö±²¥

2019-2022: Assistant Professor, IISER Mohali, India

2015-2019: Postdoctoral Researcher, University of California, San Diego, USA

2014-2015: Postdoctoral Researcher, Harvard University, USA

2008-2014: PhD, State University of New York at Albany, USA

Research interests

We study the essential processes of genome replication, repair and compaction in eukaryotic parasites belonging to the phylum Apicomplexa.
Apicomplexans cause deadly diseases like malaria (Plasmodium sp.) and toxoplasmosis (Toxoplasma sp.). These parasites affect over 200 million people worldwide each year. Our interest lies in understanding how apicomplexans carry out DNA transactions within the context of their host - specifically how these processes occur in an organelle called the 'apicoplast'. To answer this question we use electron cryomicroscopy, fast enzyme kinetics, next-generation DNA sequencing and associated biochemical and biophysical techniques.

Publications

Journal articles

  • Sarsam RD, Xu J, Lahiri I, Gong W, Li Q, Oh J, Zhou Z, Hou P, Chong J, Hao N , Li S et al (2024) . Proceedings of the National Academy of Sciences, 121(3), e2314245121. RIS download Bibtex download
  • Karasmanis EP, Reimer JM, Kendrick AA, Nguyen KHV, Rodriguez JA, Truong JB, Lahiri I, Reck-Peterson SL & Leschziner AE (2023) . Nature Structural & Molecular Biology, 30(9), 1357-1364. RIS download Bibtex download
  • Kumari A, Yadav A & Lahiri I (2022) . Biochemistry, 61(21), 2319-2333. RIS download Bibtex download
  • Bakker SE, Bergeron J, Bharadwaj A, Bhella D, Bullough P, Chau P-L, Frank RAW, Jakobi AJ, Joseph AP, Kühlbrandt W , Lahiri I et al () . Faraday Discussions, 240, 229-242. RIS download Bibtex download

Preprints

  • Stevenson SR, Tzokov SB, Lahiri I, Ayscough KR & Bullough PA (2024) , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Sarsam RD, Xu J, Lahiri I, Gong W, Oh J, Zhou Z, Chong J, Hao N, Li S, Wang D & Leschziner AE (2023) , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Leschziner A, Karasmanis E, Reimer J, Kendrick A, Rodriguez J, Truong J, Lahiri I & Reck-Peterson S (2022) , Research Square Platform LLC. RIS download Bibtex download
Research group

Ms. Anamika Kumari (BBSRC White Rose DTP PhD student)

Dr. Anjali Yadav (Postdoctoral researcher)

Teaching activities

MBB409