Martin, Chris, Dr

Qualifications

BA (Hons) Psychology (University of 91ֱ��)
PhD Neuroscience (University of 91ֱ��)
PgCert Higher Education (University of 91ֱ��).

Research interests

The main focus of my research is on the meaning of functional brain imaging signals: what do they tell us about brain activity and how might we best use this information to improve our understanding of normal brain function and neurological diseases?

I use a range of in-vivo techniques in order to uncover the neurophysiological basis of neuroimaging signals and the mechanisms of neurovascular coupling that underlie them. I am also interested in science communication, in particular the communication of brain imaging research findings beyond academic audiences and the impact of this upon public understanding of neuroscience.

Current projects in my lab are focusing on:

The roles of the neurotransmitters dopamine, serotonin and acetylcholine in modulating neuroimaging signals and neurovascular coupling.
The neuronal and neurovascular effects of transcranial direct current stimulation.
The impact of system inflammation on neurovascular coupling.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Sarmiento Soto M, Larkin JR, Martin C, Khrapitchev AA, Maczka M, Economopoulos V, Scott H, Escartin C, Bonvento G, Serres S & Sibson NR (2020) . Cancer Research.
Brezzo G, Simpson J, Ameen-Ali KE, Berwick J & Martin C (2020) . Brain, Behavior, & Immunity - Health, 5.
Sutherland B, Fordsmann J, Martin CJ, Neuhaus A, Witgen B, Piilgaard H, Lonstrup M, Couch Y, Sibson N, Lauritzen M & Buchan A (2017) . Journal of Cerebral Blood Flow and Metabolism, 37(7), 2494-2508.
Howarth C, Sutherland B, Choi HB, Martin C, Lind B, Khennouf L, LeDue J, Pakan J, Ko R, Ellis-Davies G , Lauritzen M et al (2017) . Journal of Neuroscience, 37(9), 2403-2414.
Spain A, Howarth C, Krapitchev A, Sharp T, Sibson NR & Martin C (2015) . Neuropharmacology, 99, 210-220.
Lipinski DM, Barnard AR, Singh MS, Martin C, Lee EJ, Davies WIL & MacLaren RE (2015) . Molecular Therapy, 23(8), 1308-1319.
Boorman L, Harris S, Bruyns-Haylett M, Kennerley A, Zheng Y, Martin CJ, Jones M, Redgrave P & Berwick J (2015) . Journal of Neuroscience, 35(11), 4641-4656.
Di Marco LY, Farkas E, Martin C, Venneri A & Frangi AF (2015) . Journal of Alzheimer's Disease, 46(1), 35-53.
Haensel J, Spain A & Martin CJ (2015) . Psychopharmacology, 232(3), 489-499.
Martin C (2014) . Frontiers in Neuroscience, 8.
Martin CJ, Kennerley AJ, Berwick J, Port M & Mayhew JEW (2013) . J Magn Reson Imaging, 38(3), 739-744.
Serres S, Martin CJ, Sarmiento Soto M, Bristow C, O Brien ER, Connell JJ, Khrapitchev AA & Sibson NR (2013) . International Journal of Cancer, n/a-n/a.
Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR & Anthony DC (2013) . Neuroimage, 75C, 185-194.
Singh MS, Charbel Issa P, Butler R, Martin C, Lipinski DM, Sekaran S, Barnard AR & MacLaren RE (2013) . Proc Natl Acad Sci U S A, 110, 1101-1106.
Martin C, Zheng Y, Sibson NR, Mayhew JEW & Berwick J (2013) . Neuroimage, 66, 1-8.
Li J, Bravo DS, Upton AL, Gilmour G, Tricklebank MD, Fillenz M, Martin C, Lowry JP, Bannerman DM & McHugh SB (2011) . Eur J Neurosci, 34, 1983-1996.
Zheng Y, Pan Y, Harris S, Billings S, Coca D, Berwick J, Jones M, Kennerley A, Johnston D, Martin C , Devonshire IM et al (2010) . Neuroimage, 52(3), 1135-1147.
Lefebvre V, Zheng Y, Martin C, Devonshire IM, Harris S & Mayhew JE (2009) . Neural Comput, 21(10), 2846-2868.
Jones M, Devonshire IM, Berwick J, Martin C, Redgrave P & Mayhew J (2008) . Eur J Neurosci, 27(10), 2758-2772.
Berwick J, Johnston D, Jones M, Martindale J, Martin C, Kennerley AJ, Redgrave P & Mayhew JEW (2008) . J Neurophysiol, 99(2), 787-798.
Martin C & Sibson NR (2008) . Neuropharmacology, 55, 1038-1047.
Mitchinson B, Martin CJ, Grant RA & Prescott TJ (2007) . Proc Biol Sci, 274(1613), 1035-1041.
Lefebvre VA, Zheng Y, Devonshire IM, Martin CJ & Mayhew JEW (2007) Investigating the coupling between stimulation and neural activity: a dynamic modeling approach.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 1105-1108.
Martin C (2007) . Neuroimage, 38, 1-2.
Lefebvre VA, Zheng Y, Devonshire IM, Martin CJ & Mayhew JEW (2007) . Conf Proc IEEE Eng Med Biol Soc, 2007, 1105-1108.
Martin C, Jones M, Martindale J & Mayhew J (2006) . Eur J Neurosci, 24(9), 2601-2610.
Martin C, Martindale J, Berwick J & Mayhew J (2006) . Neuroimage, 32(1), 33-48.
Martindale J, Berwick J, Martin C, Kong Y, Zheng Y & Mayhew J (2005) . J Cereb Blood Flow Metab, 25(5), 651-661.
Martindale J, Mayhew J, Berwick J, Jones M, Martin C, Johnston D, Redgrave P & Zheng Y (2003) . J Cereb Blood Flow Metab, 23(5), 546-555.
Martin C, Berwick J, Johnston D, Zheng Y, Martindale J, Port M, Redgrave P & Mayhew J (2002) . J Neurosci Methods, 120(1), 25-34.
Berwick J, Martin C, Martindale J, Jones M, Johnston D, Zheng Y, Redgrave P & Mayhew J (2002) . J Cereb Blood Flow Metab, 22(6), 670-679.

All publications

Journal articles

Johnstone KL, Blades M & Martin C (2024) . Research in Developmental Disabilities, 154, 104828-104828.
Johnstone KL, Blades M & Martin C (2021) .
Sarmiento Soto M, Larkin JR, Martin C, Khrapitchev AA, Maczka M, Economopoulos V, Scott H, Escartin C, Bonvento G, Serres S & Sibson NR (2020) . Cancer Research.
Brezzo G, Simpson J, Ameen-Ali KE, Berwick J & Martin C (2020) . Brain, Behavior, & Immunity - Health, 5.
Chhabria K, Plant K, Bandmann O, Wilkinson R, Martin C, Kugler E, Armitage P, Santoscoy P, Cunliffe V, Huisken J , Mcgown A et al (2018) . Journal of Cerebral Blood Flow and Metabolism.
Harris S, Boorman L, Das D, Kennerley A, Sharp P, Martin C, Redgrave P, Schwartz T & Berwick J (2018) . Frontiers in Neuroscience, 12.
Harris SS, Boorman L, Kennerley AJ, Sharp PS, Redgrave P, Martin C, Schwartz TH & Berwick J (2018) . NeuroImage, 171, 165-175.
De Silva S, Barnard A, Hughes S, Tam SKE, Martin CJ, Singh M, Barnea-Cramer A, McClements M, During M, Peirson S , Hankins M et al (2017) . Proceedings of the National Academy of Sciences, 114(42), 11211-11216.
Sutherland B, Fordsmann J, Martin CJ, Neuhaus A, Witgen B, Piilgaard H, Lonstrup M, Couch Y, Sibson N, Lauritzen M & Buchan A (2017) . Journal of Cerebral Blood Flow and Metabolism, 37(7), 2494-2508.
Howarth C, Sutherland B, Choi HB, Martin C, Lind B, Khennouf L, LeDue J, Pakan J, Ko R, Ellis-Davies G , Lauritzen M et al (2017) . Journal of Neuroscience, 37(9), 2403-2414.
Spain A, Howarth C, Krapitchev A, Sharp T, Sibson NR & Martin C (2015) . Neuropharmacology, 99, 210-220.
Lipinski DM, Barnard AR, Singh MS, Martin C, Lee EJ, Davies WIL & MacLaren RE (2015) . Molecular Therapy, 23(8), 1308-1319.
Boorman L, Harris S, Bruyns-Haylett M, Kennerley A, Zheng Y, Martin CJ, Jones M, Redgrave P & Berwick J (2015) . Journal of Neuroscience, 35(11), 4641-4656.
Di Marco LY, Farkas E, Martin C, Venneri A & Frangi AF (2015) . Journal of Alzheimer's Disease, 46(1), 35-53.
Haensel J, Spain A & Martin CJ (2015) . Psychopharmacology, 232(3), 489-499.
Martin C (2014) . Frontiers in Neuroscience, 8.
Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR & Anthony DC (2014) . NeuroImage, 94, 413-413.
Martin CJ, Kennerley AJ, Berwick J, Port M & Mayhew JEW (2013) . J Magn Reson Imaging, 38(3), 739-744.
Serres S, Martin CJ, Sarmiento Soto M, Bristow C, O Brien ER, Connell JJ, Khrapitchev AA & Sibson NR (2013) . International Journal of Cancer, n/a-n/a.
Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR & Anthony DC (2013) . Neuroimage, 75C, 185-194.
Singh MS, Charbel Issa P, Butler R, Martin C, Lipinski DM, Sekaran S, Barnard AR & MacLaren RE (2013) . Proc Natl Acad Sci U S A, 110, 1101-1106.
Martin C, Zheng Y, Sibson NR, Mayhew JEW & Berwick J (2013) . Neuroimage, 66, 1-8.
Li J, Bravo DS, Upton AL, Gilmour G, Tricklebank MD, Fillenz M, Martin C, Lowry JP, Bannerman DM & McHugh SB (2011) . Eur J Neurosci, 34, 1983-1996.
Couch Y, Xie Q, Martin C, Raley J, Davies A, Sibson N, Sharp T & Anthony D (2010) . Brain, Behavior, and Immunity, 24, S17-S17.
Zheng Y, Pan Y, Harris S, Billings S, Coca D, Berwick J, Jones M, Kennerley A, Johnston D, Martin C , Devonshire IM et al (2010) . Neuroimage, 52(3), 1135-1147.
Lefebvre V, Zheng Y, Martin C, Devonshire IM, Harris S & Mayhew JE (2009) . Neural Comput, 21(10), 2846-2868.
Jones M, Devonshire IM, Berwick J, Martin C, Redgrave P & Mayhew J (2008) . Eur J Neurosci, 27(10), 2758-2772.
Berwick J, Johnston D, Jones M, Martindale J, Martin C, Kennerley AJ, Redgrave P & Mayhew JEW (2008) . J Neurophysiol, 99(2), 787-798.
Martin C & Sibson NR (2008) . Neuropharmacology, 55, 1038-1047.
Martin C (2008) . Nature Medicine, 14(10), 1011-1011.
Mitchinson B, Martin CJ, Grant RA & Prescott TJ (2007) . Proc Biol Sci, 274(1613), 1035-1041.
Lefebvre VA, Zheng Y, Devonshire IM, Martin CJ & Mayhew JEW (2007) Investigating the coupling between stimulation and neural activity: a dynamic modeling approach.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 1105-1108.
Martin C (2007) . Neuroimage, 38, 1-2.
Lefebvre VA, Zheng Y, Devonshire IM, Martin CJ & Mayhew JEW (2007) . Conf Proc IEEE Eng Med Biol Soc, 2007, 1105-1108.
Martin C, Jones M, Martindale J & Mayhew J (2006) . Eur J Neurosci, 24(9), 2601-2610.
Martin C, Martindale J, Berwick J & Mayhew J (2006) . Neuroimage, 32(1), 33-48.
Martindale J, Berwick J, Martin C, Kong Y, Zheng Y & Mayhew J (2005) . J Cereb Blood Flow Metab, 25(5), 651-661.
Martindale J, Mayhew J, Berwick J, Jones M, Martin C, Johnston D, Redgrave P & Zheng Y (2003) . J Cereb Blood Flow Metab, 23(5), 546-555.
Martin C, Berwick J, Johnston D, Zheng Y, Martindale J, Port M, Redgrave P & Mayhew J (2002) . J Neurosci Methods, 120(1), 25-34.
Berwick J, Martin C, Martindale J, Jones M, Johnston D, Zheng Y, Redgrave P & Mayhew J (2002) . J Cereb Blood Flow Metab, 22(6), 670-679.
Johnstone KL, Martin C & Blades M () . Journal of Nonverbal Behavior.
Johnstone KL, Blades M & Martin C () . Memory & Cognition.
Brezzo G, Simpson J, Ameen-Ali KE, Berwick J & Martin C () .

Preprints

Johnstone KL, Martin C & Blades M (2024) , Center for Open Science.
Brezzo G, Berwick J & Martin CJ (2023) , Cold Spring Harbor Laboratory.
Johnstone KL, Blades M & Martin C (2023) , Center for Open Science.
Bolognini M & Martin C (2023) , Center for Open Science.
Brezzo G, Simpson J, Ameen-Ali KE, Berwick J & Martin C () , Research Square Platform LLC.
Harris SS, Boorman LW, Das D, Kennerley AJ, Sharp PS, Martin C, Redgrave P, Schwartz TH & Berwick J () , Cold Spring Harbor Laboratory.
Harris SS, Boorman LW, Kennerley AJ, Sharp PS, Martin C, Redgrave P, Schwartz TH & Berwick J () , Cold Spring Harbor Laboratory.

Research group

Research staff

Dr Aisling Spain

Aisling’s research is funded by a Wellcome Trust Research Project Grant and focuses on how alterations in the functioning of the serotonin neurotransmitter system in the brain affect functional brain imaging signals and their relationship to neuronal activity.

Miss Elizabeth Kirkham

Lizzy's research is funded by the British Academy and investigates how neuroscience can improve the effectiveness of behaviour change interventions (with respect to both intervention design and evaluation) with a specific focus on interventions to tackle obesity.

Postgraduate students

Melissa Maczka

University of Oxford Doctoral Training Centre Student on the Life Sciences Interface Program. Melissa’s project involves developing new mathematical tools to help us understand what functional brain imaging signals tell us about the activity of neurons in the brain.

Jointly supervised by Dr Jonathan Marchini (Statistics, University of Oxford) and Dr Mark Woolrich (Department of Psychiatry, University of Oxford).

Gaia Brezzo

Department of Psychology PhD Teaching Fellowship. Gaia is investigating how neurodegenerative brain disease alters the relationship between neuronal activity and blood flow in the brain.

This will improve our understanding of how to best use functional brain imaging tools in clinical populations as well as providing insights into the role of neurovascular mechanisms in disease progression.

Anka Gorgiev

South Eastern European Research Centre PhD Studentship in collaboration with 91ֱ�� and City College (International Faculty of 91ֱ��), Thessolaniki, Greece.

Anka's PhD in in the area of Neuromarketing and specifically addresses the issue of whether or not emerging technologies and theoretical developments in neuroscience are driving a 'paradigm shift' in marketing.

Grants

2015-2019 91ֱ�� Interdisciplinary PhD Network Award. "Neuroimaging in Cardiovascular Disease (NICAD) Network". C Martin (PI), Department of Psychology / Department of Cardiovascular Science / 91ֱ�� Institute for Translational Neuroscience.
2015-2018 Medical Research Council Research Grant. "Investigating the thermoregulatory role of neurovascular coupling and the anti-epileptogenic and neuroprotective effects of focal cerebral cooling". Berwick J (PI), Harris S, Martin C, Redgrave P, Boorman L, Kennerley A. £558K (FEC), 36 Months.
2014-2017 Royal Society University Research Fellowship (Renewal) "Dopamine, Brain Imaging Signals, and Neurovascular Coupling." £341K, 36 Months.
2013 British Academy/Leverhulme Trust Small Research Grant “Improving cross-disciplinary research and practice in health psychology: What can neuroscience do for the design of behaviour change interventions to improve health? A systematic review." J Martin (PI) & C Martin, £9899, 12 Months.
2011-2015 Wellcome Trust Research Grant. “Neuropharmacological modulation of functional brain imaging signals in awake and anaesthetized rats”. Chris Martin (PI), £257K, 36 Months.
2011-2016 MRC & BBSRC. “The neurophysiological basis of negative BOLD signals”. Berwick J (PI), Jones M, Kennerley A, Boorman L, Martin C, Redgrave P, Zheng Y., £655K, 36 Months.
2010 John Fell Fund Award. “Combining optogenetic modulation of neuronal activity with functional magnetic resonance imaging: establishing a new methodological resource for investigating CNS circuits.” Chris Martin (PI), N. Sibson, D. Bannerman, N. Rawlins and T. Sharp, £14K.
2010 John Fell Fund Award. “Early career researcher laboratory start-up support: funding request for equipment to establish functional MRI research in conscious rats”. Chris Martin (PI), £16K.
2010 Doctoral Training Centre Funding for DPhil student (Main Supervisor), jointly supervised with Mark Woolrich (FMRIB) and Jonathan Marchini (Statistics).
2009-2014 Royal Society University Research Fellowship. “Neuropharmacological modulation of functional brain imaging signals.” Chris Martin (PI), £641K, 60 Months.
2009 Young Scientist Travel Award (£2000) from the International Society for Cerebral Blood Flow and Metabolism to attend and present at the 2009 annual meeting in Chicago.
2005-2008 Medical Research Council Research Grant. “The neural and haemodynamic basis of the fMRI BOLD signal: An awake animal model for functional imaging research.” John Mayhew (PI), Chris Martin (application written by myself based on my PhD research). £240K, 36 Months.
2002 Department of Psychology Bursary (£500) to present research at Society for Neurosciences 2002 Conference (Orlando).
2000 Awarded Medical Research Council Studentship to fund PhD.

Professional activities and memberships

Departmental roles

MSc Systems Neuroscience Course Director
Director of Postgraduate Research Studies
Equality and Diversity Committee Member
Research Committee Member
Psychology Management Group Member

91ֱ��

School of Psychology

School of Psychology

Dr Chris Martin

Featured publications

Journal articles

All publications

Journal articles

Preprints

Research staff

Dr Aisling Spain

Miss Elizabeth Kirkham

Postgraduate students

Melissa Maczka

Gaia Brezzo

Anka Gorgiev

Departmental roles

91ֱ��

School of Psychology

School of Psychology

Dr Chris Martin

Featured publications

Journal articles

All publications

Journal articles

Preprints

Research staff

Dr Aisling Spain

Miss Elizabeth Kirkham

Postgraduate students

Melissa Maczka

Gaia Brezzo

Anka Gorgiev

Departmental roles

Links