Mike Bradburn
MSc
Population Health, School of Medicine and Population Health
Senior Medical Statistician
+44 114 222 0706
Full contact details
Population Health, School of Medicine and Population Health
Room 3.06, 3rd Floor
Regent Court (ScHARR)
30 Regent Street
91Ö±²¥
S1 4DA
- Profile
-
I joined the CTRU in 2007, having previously worked as a statistician at Cancer Research UK and PAREXEL International. In my current role I oversee the statistical input and conduct of the CTRU's portfolio of clinical studies.
I am currently involved in the following projects:
- ASTIClite - Autologous Stem cell Transplantation in refractory Crohn's disease
- COMMEND - COMmitment therapy for people with Motor nEuroN Disease
- HighCALS - A programme to develop and evaluate a complex intervention to improve nutritional management for people with Amyotrophic Lateral Sclerosis (ALS)
- OPTION-DM - Optimal Pathway for Treating neuropathic paiN in Diabetes Mellitus
- PANDA - A Practical Adaptive & Novel Design and Analysis (PANDA) Toolkit
- PHEWS - Pre-Hospital Early Warning scores for Sepsis study
- PITSTOP - PIlonidal sinus Treatment: STudying the OPtions
- VTEAM - Venous Thromboembolism Assessment Model Study
- Research interests
-
I am currently involved in the following projects:
CONTACT-GAD - A randomised CONtrolled trial of Tailored Acceptance and Commitment Therapy for older people with treatment resistant Generalised Anxiety Disorder (NIHR134141)
DENIM - Delivering Effective Non-Invasive ventilation in Motor neuron disease using intensive remote support (NIHR158715)
E-IMMUNE - Empowerment of patients and clinicians in the management of immunotherapy toxicity through a new digital care pathway (YCR PIONEER).
EVIDENT - The Ex-VIvo DEtermined caNcer therapy study (YCR PIONEER)
HighCALS - A programme to develop and evaluate a complex intervention to improve nutritional management for people with Amyotrophic Lateral Sclerosis (NIHR RP-PG-1016-2006)
TONIC - Timing Of Nutrition In emergenCy laparotomy (NIHR155875)
- Publications
-
Show: Featured publications All publications
Featured publications
Journal articles
All publications
Journal articles
- . The Cognitive Behaviour Therapist, 17, e36.
- . The Lancet.
- . Colorectal Disease.
- . European Journal of Neurology.
- . Colorectal Disease.
- . British Journal of Surgery, 111(3), znae009.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . The Lancet Gastroenterology and Hepatology.
- . Clinical Oncology.
- . Clinical Trials, 17407745231204036.
- . British Journal of Anaesthesia.
- . British Journal of Cancer, 129(10), 1599-1607.
- . Emergency Medicine Journal.
- . Obstetric Anesthesia Digest, 43(3), 152-153.
- . Pilot and Feasibility Studies, 9.
- . BMJ Open, 13(2), e069244-e069244.
- . The Lancet, 401(10372), 192-193.
- . Colorectal Disease.
- . Annals of The Royal College of Surgeons of England.
- . BMC Neurology, 22(1).
- . Techniques in Coloproctology.
- . The Lancet, 400(10363), 1597-1606.
- . The Lancet, 400(10353), 680-690.
- . British Journal of Anaesthesia.
- . Health Technology Assessment, 26(28).
- . Modern Pathology.
- . JAMA Network Open, 5(1).
- . Health Science Reports, 4(4).
- . Radiotherapy and Oncology, 161, 166-176.
- . Trials, 22(1).
- . Chest.
- . Pituitary.
- . The Lancet Psychiatry.
- . British Journal of Cancer.
- . Value in Health.
- . Journal of Human Nutrition and Dietetics.
- . Colorectal Disease.
- . British Journal of Surgery, 108(3), 315-325.
- . British Journal of Surgery.
- . European Journal of Cancer, 144, 269-280.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . BMC Emerg Med, 21(1), 13.
- . European Journal of Cancer, 142, 48-62.
- . J Geriatr Oncol.
- . British Paramedic Journal, 5(3), 15-22.
- . Journal of Geriatric Oncology.
- . Colorectal Disease.
- . BMJ Open, 10(7).
- . Journal of Clinical Epidemiology.
- . Trials, 21.
- . BMJ Open, 9(7).
- . European Journal of Surgical Oncology, 45(12), 2319-2324.
- . BMC Gastroenterology, 19(1).
- . The Lancet Child and Adolescent Health.
- . BMC Psychiatry, 19(1).
- . Trials, 20(1).
- . BMJ Open, 9.
- . BMJ Open, 9(10).
- . Health Technology Assessment, 23(49), 1-144.
- . British Journal of Health Psychology.
- . Clinical Radiology, 74(7), 527-533.
- . Journal of Surgical Research, 238, 23-28.
- . BJS Open.
- . BJOG: An International Journal of Obstetrics & Gynaecology, 126(3), 383-392.
- . Pilot and Feasibility Studies, 4.
- . Trials, 19(1), 578-578.
- . The British journal of psychiatry : the journal of mental science.
- . Pilot and Feasibility Studies, 4(1).
- . European Radiology, 29(1), 195-201.
- . Osteoporosis International, 29(6), 1407-1417.
- . BMJ Open, 8(4), ---.
- . Journal of Neurology, Neurosurgery, and Psychiatry, 89, 248-255.
- . Clinical Radiology, 73(2), 123-134.
- . Ultrasound in Obstetrics and Gynecology, 50(6), 745-752.
- . Ultrasound in Obstetrics & Gynecology, 50(6), 736-744.
- . Journal of Clinical Epidemiology, 92, 116-125.
- . BMJ Open, 7(10).
- . Obstetrical & Gynecological Survey, 72(6), 323-325.
- . Clinical Radiology.
- . European Radiology, 27(6), 2367-2380.
- . Trials(203).
- . PharmacoEconomics Open.
- . Ultrasound in Obstetrics & Gynecology.
- . BMJ, 356.
- . RMD Open, 3(1).
- . Trials, 18(1), 93-93.
- . Cochrane Database of Systematic Reviews, 2016(12).
- . The Lancet, 389(10068), 538-546.
- . Health Technology Assessment, 20(90).
- . Health Technology Assessment, 20(88), 1-180.
- . Health Technology Assessment, 20(93), 1-154.
- . The Lancet, 388(10042), 356-364.
- . Health Technol Assess, 20(45), 1-186.
- . European Journal of Neurology, 23(6), 1071-1078.
- . Diabetic Medicine, 33(2), 243-251.
- . BMC Pulmonary Medicine, 15(1).
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(7-8), 448-455.
- . Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 23(1).
- . The Lancet Neurology, 14(9), 883-892.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(7-8), 478-484.
- . Journal of Clinical Epidemiology, 68(3), 347-354.
- . Health Services and Delivery Research, 3(1).
- . Clinical Radiology, 70(3), 248-253.
- . Thorax, 69(12), 1105-1112.
- . The Journal of Clinical Endocrinology & Metabolism, 99(12), 4462-4470.
- . BMC Psychiatry, 14, 5.
- . Diabetes Research and Clinical Practice, 106(3), 443-450.
- . Emerg Med J, 31(e1), e40-e45.
- . Health Technol Assess, 18(22), 1-168.
- . BMC Psychiatry, 13, 321.
- . J Foot Ankle Res, 6(1), 40.
- . Trials, 14(1).
- . The Lancet Respiratory Medicine, 1(4), 293-300.
- . Eur J Prev Cardiol, 20(1), 107-120.
- . J Bone Miner Res, 27(11), 2314-2324.
- . BMC Gastroenterol, 12, 153.
- . Amyotroph Lateral Scler, 13(6), 528-532.
- . Health Qual Life Outcomes, 10, 20.
- . Health and Social Care in the Community, 20(5), 537-549.
- . BMC Neurol, 12, 74.
- . Heart, 98(4), 312-318.
- . Osteoporosis International, 1-14.
- . Heart, 98(4), 312-318.
- . Emergency Medicine Journal, 29(3), 233-238.
- . Am J Emerg Med, 30(1), 37-44.
- . Emerg Med J, 29(1), 47-53.
- . Acad Emerg Med, 18(5), 488-495.
- . Archives of Disease in Childhood, 96(7), 658-663.
- . Osteoporosis International, 22(10), 2721-2731.
- . Heart, 97(3), 190-196.
- . Br J Clin Psychol, 49(Pt 4), 473-489.
- Looking inside the black box of community rehabilitation and intermediate care teams in the United Kingdom: an audit of service and staffing.. Qual Prim Care, 17(5), 323-333.
- . International Journal of Therapy and Rehabilitation, 15(9), 374-375.
- metan: fixed- and random-effects meta-analysis. STATA J, 8(1), 3-28.
- . Stat Med, 26(1), 53-77.
- Indirect comparisons of competing interventions. HEALTH TECHNOL ASSES, 9(26), 1-+.
- . PATIENT EDUC COUNS, 58(1), 13-26.
- . Br J Haematol, 129(6), 746-754.
- . BRIT J HAEMATOL, 129(1), 35-44.
- . Blood, 104(11), 165-165.
- . Nicotine Tob Res, 6(5), 769-776.
- . CANCER, 100(10), 2148-2153.
- . Studies in Health Technology and Informatics, 107, 197-201.
- . Breast Cancer Research, 5(6), R242-R249.
- Do men and women differ in response to nicotine replacement therapy: A meta-analysis. NICOTINE TOB RES, 5(5), 787-788.
- . Br J Cancer, 89(5), 781-786.
- . Br J Cancer, 89(4), 605-611.
- . Br J Cancer, 89(3), 431-436.
- . Br J Cancer, 89(2), 232-238.
- Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer: association with prognosis. EUR J CANCER, 37(18), 2405-2412.
- Reducing community dyspepsia drug costs: a controlled trial. GUT, 49(4), 495-501.
- . Hematology, 6(3), 163-175.
- High-dose treatment with autologous bone marrow support as consolidation of first remission in younger patients with acute myelogenous leukaemia. ANN ONCOL, 11(8), 1007-1015.
- Overexpression of H-Ryk in epithelial ovarian cancer: Prognostic significance of receptor expression. CLIN CANCER RES, 6(8), 3271-3281.
- Teaching non-specialist health care professionals how to identify the atypical mole syndrome phenotype: a multinational study. BRIT J DERMATOL, 142(2), 331-337.
- High-dose therapy with autologous bone marrow support as consolidation of remission in follicular lymphoma: Long-term clinical and molecular follow-up. J CLIN ONCOL, 18(3), 527-536.
- . Br J Haematol, 108(2), 455-457.
- Immunocytoma: A retrospective analysis from St Bartholomew's Hospital - 1972 to 1996. J CLIN ONCOL, 17(9), 2847-2853.
- Patterns of outcome following recurrence after myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma. J CLIN ONCOL, 17(1), 216-221.
- . The Journal of Urology, 1932-1932.
- . Journal of Urology, 160(5), 1932-1932.
- . BMJ, 317(7165), 1041-1046.
- Detection of residual disease following breast-conserving surgery. BRIT J SURG, 85(9), 1273-1276.
- . Br J Cancer, 77(11), 1944-1949.
- Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer.. Cancer Res, 57(23), 5281-5285.
- . Health Technology Assessment, 1-113.
- . Health Technology Assessment, 1-93.
- . Efficacy and Mechanism Evaluation, 1-106.
- . Health Technology Assessment, 26(39), 1-100.
- Temporal Association Between Invasive Procedures and Infective Endocarditis. Heart.
- . Programme Grants for Applied Research, 10(6), 1-114.
- . Health Technology Assessment, 25(7), 1-92.
- . PLOS ONE, 16(1), e0245840-e0245840.
- . The Hematology Journal, 3(5), 237-243.
- . The Hematology Journal, 1(6), 367-373.
- . Archives of Disease in Childhood - Fetal and Neonatal Edition.
- .
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Health Technology Assessment, 19(66), 1-130.
Chapters
- Sweetening the pill: Compliance and clinical trials In Davies M & Kermani F (Ed.), Patient Compliance: Sweetening the Pill (pp. 109-132). Gower Publishing Ltd
- In Egger M, Smith GD & Altman DG (Ed.), Systematic Reviews in Health Care (pp. 347-372). Wiley-Blackwell
- In Egger M, Smith GD & Altman DG (Ed.), Systematic Reviews in Health Care: Meta-Analysis in Context (pp. 285-312). Wiley-Blackwell
Conference proceedings papers
- . Value in Health, Vol. 25(12 Suppl) (pp S461-S461). Vienna, Austria, 6 November 2022 - 9 November 2022.
- . Clinical Nutrition ESPEN, Vol. 48 (pp 510-510). Brighton, UK, 30 November 2021 - 1 December 2021.
- Application of the Target Trial Framework for Estimating Comparative Effectiveness Using Real-World Data - A Systematic Review. VALUE IN HEALTH, Vol. 25(12) (pp S461-S461)
- . Annals of Oncology, Vol. 31 (pp S318-S319)
- . Poster Session Abstracts
- Bridging the age gap in breast cancer: optimisation of survival and quality of life outcomes in older women with early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, Vol. 180(2) (pp 594-594)
- . British Paramedic Journal, Vol. 4(3) (pp 53-54). Cardiff, Wales, 24 September 2019 - 24 September 2019.
- . Trials, Vol. 20(Suppl 1) (pp 53-54). Brighton, UK, 6 October 2019 - 9 October 2019.
- . Trials, Vol. 20(Supplement 1) (pp 124-124). Brighton, UK, 6 October 2019 - 9 October 2019.
- . Clinical Nutrition ESPEN, Vol. 29 (pp 265-266)
- . Journal of the Neurological Sciences, Vol. 381 (pp 102-102)
- . Studies in Health Technology and Informatics, Vol. 242 (pp 152-159)
- . 1.6 General Practice and Primary Care
- ULTRASOUND COMPARED WITH BIOPSY IN THE DIAGNOSIS OF SUSPECTED GIANT CELL ARTERITIS. RHEUMATOLOGY, Vol. 55 (pp 37-37)
- INTERRATER AND INTRARATER ANALYSIS OF ULTRASOUND AND HISTOLOGICAL FINDINGS IN PATIENTS WITH SUSPECTED GIANT CELL ARTERITIS. RHEUMATOLOGY, Vol. 55 (pp 171-171)
- Elevated creatine kinase is associated with a better prognosis in patients with amyotrophic lateral sclerosis. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 741-741)
- Effects of cough augmentation on pulmonary morbidity, survival, and quality of life in patients with amyotrophic lateral sclerosis in respiratory failure: a randomised trial. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 244-244)
- . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(10) (pp e4.93-e4)
- Late-breaking abstract: Hypertonic saline in acute bronchiolitis: Randomised controlled trial (RCT) and economic evaluation (the SABRE study). EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- . J Neurol Neurosurg Psychiatry, Vol. 84(11) (pp e2). England
- . J Neurol Neurosurg Psychiatry, Vol. 84(11) (pp e2). England
- . Trials, Vol. 12 Suppl 1 (pp A26)
- (YOUNG INVESTIGATOR AWARD) HIP STRUCTURE ANALYSIS OF HIP QCT SCANS AND HIP FRACTURE RISK IN OLDER MEN. OSTEOPOROSIS INTERNATIONAL, Vol. 21 (pp S455-S455)
- The RATPAC Trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers): a randomised controlled trial of point-of-care cardiac markers in the emergency department. EUROPEAN HEART JOURNAL, Vol. 31 (pp 947-947)
- Early response to induction is predictive of survival in childhood Philadelphia chromosome positive acute lymphoblastic leukaemia: Results of the Medical Research Council ALL 97 trial.. BLOOD, Vol. 104(11) (pp 51A-51A)
- Outcome of Philadelphia positive (Ph+) childhood acute lymphoblastic leukaemia (ALL) on the MRC ALL 97/01 trial. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 125 (pp 1-1)
- Genetic risk factor for follicular lymphoma within the MHC region.. BLOOD, Vol. 100(11) (pp 567A-567A)
- . Annals of Oncology, Vol. 11 (pp S117-S121)
- Treatment of mantle-cell lymphoma with Rituximab (chimeric monoclonal anti-CD20 antibody): Analysis of factors associated with response. ANNALS OF ONCOLOGY, Vol. 11 (pp 117-121)
- An analysis of factors which predict failure to mobilize peripheral blood progenitor cells (PBPC) with G-CSF alone in patients with non-Hodgkion's lymphoma.. BRIT J CANCER, Vol. 80 (pp 64-64)
- . Rheumatology
Reports
Posters
- Lessons learnt from a multi-centre type 3 surgical trial. 5th International Clinical Trials Methodology Conference (ICTMC 2019).
- Challenges in the design, planning and implementation of trials evaluating group interventions.
- ePS5.05 Understanding objective adherence to preventative inhaled therapies at a centre level for quality improvement - a CFHealthHub (CFHH) improvement collaborative study.
- #20 Design and rationale of the PIlonidal sinus Treatment - STudying the OPtions (PITSTOP) study: a multicentre cohort, nested mixed-methods case study and discrete choice experiment (poster presentation).
Other
- . The Lancet, 388(10063), 2996-2996.
- . The Lancet Neurology, 15(6), 543-544.
- . Osteoporosis International, 22(10), 2733.
- . NICOTINE TOB RES, 6(5), 865-867.
- Randomised trials useful to find best methods of enhancing clinical practice. BRIT MED J, 318(7194), 1353-1353.
Preprints
- Research group
-
DTS
- Professional activities and memberships
-
- Committee member for the NIHR HTA Commissioned Calls funding panel
- Committee member for the UKCRC CTU network statistics operations group and TMRP statistical analysis working group
- Chair of three trial Data Monitoring Committees and a member for six Trial Steering Committees