Walsh, Jennifer, Professor

Professor Jennifer Walsh

MBChB, PhD, FRCP, FHEA

Clinical Medicine, School of Medicine and Population Health

Professor of Clinical Education

MBChB Programme Director

j.walsh@sheffield.ac.uk
+44 114 215 9702

+44 114 215 9236

+44 114 261 8775 (Fax)

Metabolic Bone Centre, Sorby Wing, Northern General Hospital

Full contact details

Professor Jennifer Walsh
Clinical Medicine, School of Medicine and Population Health
Metabolic Bone Centre, Sorby Wing
Northern General Hospital
Herries Road
91ֱ��
S5 7AU

Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I trained in Endocrinology in 91ֱ��, and completed my PhD on Determinants of Peak Bone Mass and Bone Size in 2008, funded by an Arthritis Research UK clinical fellowship. I was appointed as a Senior Clinical Lecturer in 2014.

My clinical interests are in young adult bone disease and endocrinology. I am director of Student Affairs for the 91ֱ�� MBChB.

Research interests

My research interests are in bone microarchitecture in skeletal maturation and ageing, the interactions of fat and bone, and treatment of osteoporosis and other metabolic bone diseases. I am currently leading clinical studies of vitamin D physiology and a clinical trial of selenium for osteoporosis, and I am a co-investigator in the TOPaZ trial in osteogenesis inperfecta.

Current projects

Physiology of high dose vitamin D dosing
The effects of gender and age on bone microarchitecture
The effects of obesity on bone and muscle
Bone loss in prostate cancer treatment
Selenium treatment for osteoporosis
TOPaZ trial in osteogenesis imperfecta

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Walsh JS, Jacques RM, Schomburg L, Hill TR, Mathers JC, Williams GR & Eastell R (2021) . The Lancet Healthy Longevity, 2(4), e212-e221.
Walsh JS, Marshall H, Smith IL, Greenfield DM, Swain J, Best E, Ashton J, Brown JM, Huddart R, Coleman RE , Snowden JA et al (2019) . PLOS Medicine, 16(11), ---.
Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS , Schoenmakers I et al (2018) . The Journal of Clinical Endocrinology & Metabolism, 103(9), 3278-3288.
Naylor KE, Bradburn M, Paggiosi MA, Gossiel F, Peel NFA, McCloskey EV, Walsh JS & Eastell R (2018) . Osteoporosis International, 29(6), 1407-1417.
Walsh JS, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Jacques R & Eastell (2016) . American Journal of Clinical Nutrition, 103(6), 1465-1471.
Evans AL, Paggiosi MA, Eastell R & Walsh JS (2015) . Journal of Bone and Mineral Research, 30(5), 920-928.
Walsh JS, Newell-Price JD, DeBono M, Adaway J, Keevil B & Eastell R (2013) . J Clin Endocrinol Metab, 98(7), 2902-2907.
Walsh JS, Paggiosi MA & Eastell R (2012) . J Clin Endocrinol Metab, 97(9), 3342-3348.
Walsh JS & Henriksen DB (2010) . Arch Biochem Biophys, 503(1), 11-19.
Walsh JS, Henry YM, Fatayerji D & Eastell R (2009) . Osteoporos Int, 20(3), 355-362.
Walsh JS, Eastell R & Peel NFA (2008) . J Clin Endocrinol Metab, 93(4), 1317-1323.

All publications

Journal articles

Perri G, Mathers JC, Martin-Ruiz C, Parker C, Demircan K, Chillon TS, Schomburg L, Robinson L, Stevenson EJ, Shannon OM , Muniz-Terrera G et al (2024) . The American Journal of Clinical Nutrition, S0002-9165(24)00735.
Handforth C, Paggiosi MA, Jacques R, Gossiel F, Eastell R, Walsh JS & Brown JE (2024) . Journal of Bone Oncology, 47.
Lin Z, Henson WH, Dowling L, Walsh J, Dall’Ara E & Guo L (2024) . Frontiers in Bioengineering and Biotechnology, 12.
Perri G, Mathers JC, Martin-Ruiz C, Walsh JS, Eastell R, Schomburg L, Robinson L, Chillon T, Demircan K, Parker C & Hill TR (2023) . Proceedings of the Nutrition Society, 82(OCE5), e369.
Hald JD, Keerie C, Weir CJ, Javaid MK, Lam W, Osborne P, Walsh J, Langdahl BL & Ralston SH (2023) . BMJ Open, 13(11), e078164-e078164.
Perri G, Mathers JC, Martin-Ruiz C, Walsh JS, Eastell R, Schomburg L, Robinson L & Hill TR (2023) . Proceedings of the Nutrition Society, 82(OCE3).
Mattia L, Gossiel F, Walsh JS & Eastell R (2023) . Bone Reports, 18, 101676-101676.
Kamenicky P, Briot K, Brandi ML, Cohen-Solal M, Crowley RK, Keen R, Kolta S, Lachmann RH, Lecoq A-L, Ralston SH , Walsh JS et al (2023) . RMD Open, 9(1).
Dowling L, Cuthbertson DJ & Walsh JS (2022) . Obesity.
Vilaca T, Evans A, Gossiel F, Paggiosi M, Eastell R & Walsh JS (2022) . European Journal of Endocrinology, 187(6), 743-750.
Mattia L, Gossiel F, Wang JY, Amin I, Kennedy MG, Walsh J & Eastell R (2022) . Bone Reports, 16.
Harvey NC, Poole KE, Ralston SH, McCloskey EV, Sangan CB, Wiggins L, Jones C, Gittoes N, Compston J, Abrahamsen B , Gregson C et al (2022) . Archives of Osteoporosis, 17(1).
Dowling L, Duseja A, Vilaca T, Walsh JS & Goljanek‐Whysall K (2022) . Journal of Cachexia, Sarcopenia and Muscle.
Schini M, Peel N, Toronjo-Urquiza L, Thomas E, Salam S, Khwaja A, Eastell R & Walsh JS (2021) . Osteoporosis International.
Orlando G, Clarke S, Roy M, Lachmann R, Walsh J, Schini M, Kassim J & Ireland A (2021) . Bone Reports, 14.
Vilaca T, Paggiosi M, Walsh JS, Selvarajah D & Eastell R (2021) . Journal of Bone and Mineral Research.
Walsh JS, Jacques RM, Schomburg L, Hill TR, Mathers JC, Williams GR & Eastell R (2021) . The Lancet Healthy Longevity, 2(4), e212-e221.
Walsh JS, Jacques R, Schomburg L, Hill T, Mathers J, Williams G & Eastell R (2021) . Efficacy and Mechanism Evaluation, 8(6).
Desborough R, Nicklin P, Gossiel F, Balasubramanian M, Walsh JS, Petryk A, Teynor M & Eastell R (2021) . Bone, 144.
Du J, Hartley C, Brooke-Wavell K, Paggiosi MA, Walsh JS, Li S & Silberschmidt VV (2020) . Osteoporosis International.
Paggiosi MA, Peel N, McCloskey E, Walsh JS & Eastell R (2020) . Bone Reports, 13.
Vilaca T, Paggiosi M, Walsh J, Selvarajah D & Eastell R (2020) . Bone Reports, 13.
Schini M, Hannan F, Walsh J & Eastell R (2020) . Bone Reports, 13.
Fontalis A, Gossiel F, Schini M, Walsh J & Eastell R (2020) . Bone Reports, 13.
Schini M, Jacques R, Oakes E, Peel N, Walsh JS & Eastell R (2020) . European Journal of Endocrinology.
Brown JE, Handforth C, Compston JE, Cross W, Parr N, Selby P, Wood S, Drudge-Coates L, Walsh JS, Mitchell C , Collinson FJ et al (2020) . Journal of Bone Oncology, 100311-100311.
Perri G, Mendonça N, Jagger C, Walsh J, Eastell R, Mathers JC & Hill TR (2020) . Nutrients, 12(7).
Mickute G, Staley K, Delaney H, Gardiner O, Hunter A, Keen R, Lockhart L, Meade N, Newman M, Ralston S , Rush E et al (2020) . Orphanet Journal of Rare Diseases, 15(1).
Schini M, Stirling R, Jacques R, Oakes E, Peel N, Walsh J & Eastell R (2020) . Clinical Endocrinology.
Schini M, Jacques R, Oakes E, Peel N, Walsh J & Eastell R (2020) . The Journal of Clinical Endocrinology & Metabolism, 105(4).
Paggiosi MA, Debono M, Walsh JS, Peel NFA & Eastell R (2020) . Osteoporosis International, 31(4), 667-675.
Gossiel F, Paggiosi MA, Naylor KE, McCloskey EV, Walsh J, Peel N & Eastell R (2020) . Bone, 131.
Walsh JS, Marshall H, Smith IL, Greenfield DM, Swain J, Best E, Ashton J, Brown JM, Huddart R, Coleman RE , Snowden JA et al (2019) . PLOS Medicine, 16(11), ---.
Du J, Brooke-Wavell K, Paggiosi MA, Hartley C, Walsh JS, Silberschmidt VV & Li S (2019) . BONE, 121, 139-148.
Naylor KE, McCloskey EV, Jacques RM, Peel NFA, Paggiosi MA, Gossiel F, Walsh JS & Eastell R (2019) . Osteoporosis International.
Vilaca T, Walsh J & Eastell R (2019) . Osteoporosis International, 30(1), 135-143.
Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS , Schoenmakers I et al (2018) . The Journal of Clinical Endocrinology & Metabolism, 103(9), 3278-3288.
Gopal-Kothandapani JS, Evans LF, Walsh JS, Gossiel F, Rigby AS, Eastell R & Bishop NJ (2018) . Clinical Endocrinology.
Naylor KE, Bradburn M, Paggiosi MA, Gossiel F, Peel NFA, McCloskey EV, Walsh JS & Eastell R (2018) . Osteoporosis International, 29(6), 1407-1417.
Eastell R & Walsh JS (2018) . Nature Reviews Endocrinology, 14(5), 255-256.
Paggiosi MA, Yang L, Blackwell D, Walsh JS, McCloskey E, Peel N & Eastell R (2018) . Osteoporosis International, 29(6), 1367-1378.
Gossiel F, Scott JR, Paggiosi MA, Naylor KE, McCloskey EV, Peel NFA, Walsh JS & Eastell R (2018) . Journal of Clinical Endocrinology and Metabolism.
Eastell R, Pigott T, Gossiel F, Naylor KE, Walsh JS & Peel NFA (2018) . European Journal of Endocrinology, 178(1), R19-R31.
Walsh JS, Bowles S & Evans AL (2017) . Current Opinion in Endocrinology & Diabetes and Obesity, 24, 389-394.
Eastell R & Walsh JS (2017) . Clinical Cases in Mineral and Bone Metabolism, 14(2), 173-178.
Walsh JS, Gossiel F, Scott JR, Paggiosi MA & Eastell R (2017) . Bone, 99, 8-13.
Walsh JS & Vilaca T (2017) . Calcif Tissue Int.
Walsh JS (2017) . Surgery (United Kingdom), 36(1), 1-6.
Walsh J, Gittoes N & Selby P (2016) . Endocrine Connections, 5(5), G9-G11.
Adaway JE, Dobson R, Walsh J, Cuthbertson DJ, Monaghan PJ, Trainer PJ, Valle JW & Keevil BG (2016) . Annals of Clinical Biochemistry, 53(5), 554-560.
Gossiel F, Hoyle C, McCloskey EV, Naylor KE, Walsh J, Peel N & Eastell R (2016) . Bone, 92, 94-99.
Walsh JS, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Jacques R & Eastell (2016) . American Journal of Clinical Nutrition, 103(6), 1465-1471.
Naylor KE, Jacques RM, Paggiosi M, Gossiel F, Peel NFA, McCloskey EV, Walsh JS & Eastell R (2016) . Osteoporosis International, 27(1), 21-31.
Naylor KE, Jacques RM, Paggiosi M, Gossiel F, Peel NF, McCloskey EV, Walsh JS & Eastell R (2016) . Osteoporosis International, 27(1), 37-37.
Greenfield DM, Blewitt A, Coleman RE, Walsh JS, Snowden JA, Ross RJM & Han TS (2016) . Clinical Endocrinology, 84(2), 296-304.
Smith I, Swain J, Marshall H, Smith A, Walsh J, Ross R & Brown S (2015) . Trials, 16(S2).
Evans AL, Paggiosi MA, Eastell R & Walsh JS (2015) . Journal of Bone and Mineral Research, 30(5), 920-928.
Dimitri P, Jacques RM, Paggiosi M, King D, Walsh J, Taylor ZA, Frangi AF, Bishop N & Eastell R (2015) . The Journal of Clinical Endocrinology & Metabolism, 100(2), 594-602.
Swain J, Smith I, Smith A, Walsh J, Ross R & Marshall H (2015) . Trials, 16(S2).
Walsh JS (2015) . Surgery (Oxford), 33(1), 1-6.
Paggiosi MA, Peel N, McCloskey E, Walsh JS & Eastell R (2014) . Osteoporosis International, 25(12), 2729-2741.
Bishop NJ & Walsh JS (2014) . Journal of Clinical Investigation, 124(2), 476-477.
Paggiosi MA, Eastell R & Walsh JS (2014) . Calcif Tissue Int, 94(2), 191-201.
Walsh JS & Eastell R (2013) . Nat Rev Endocrinol, 9(11), 637-645.
Eastell R & Walsh JS (2013) . Lancet, 382(9886), 5-7.
Walsh JS, Newell-Price JD, DeBono M, Adaway J, Keevil B & Eastell R (2013) . J Clin Endocrinol Metab, 98(7), 2902-2907.
Walsh JS & Eastell R (2013) . J Clin Endocrinol Metab, 98(2), 519-521.
Walsh JS, Paggiosi MA & Eastell R (2012) . J Clin Endocrinol Metab, 97(9), 3342-3348.
Walsh JS, Newman C & Eastell R (2012) . Trends Endocrinol Metab, 23(4), 163-168.
Dimitri P, Bishop N, Walsh JS & Eastell R (2012) . Bone, 50(2), 457-466.
Smith CM, Wright NP, Wales JKH, MacKenzie C, Primhak RA, Eastell R & Walsh JS (2011) . Clinical Endocrinology, 75(4), 443-449.
Eastell R, Walsh JS, Watts NB & Siris E (2011) . Bone, 49(1), 82-88.
Walsh JS & Henriksen DB (2010) . Arch Biochem Biophys, 503(1), 11-19.
Walsh JS, Eastell R, Coleman RE, Snowden JA, Shalet SM, Ross RJ & Greenfield DM (2010) . Bone, 47, S189-S190.
Walsh JS, Henry YM, Fatayerji D & Eastell R (2010) . Clin Endocrinol (Oxf), 72(3), 320-327.
Walsh JS, Eastell R & Peel NF (2010) . Fertil Steril, 93(3), 697-701.
Coleman RE & Walsh JS (2010) . NAT REV ENDOCRINOL, 6(1), 10-12.
Walsh JS, Henry YM, Fatayerji D & Eastell R (2009) . Osteoporos Int, 20(3), 355-362.
Walsh J & Eastell R (2009) Effects of Feeding on Bone Metabolism. Clinical Reviews in Bone and Mineral Metabolism, 7(3), 230-239.
Walsh JS, Eastell R & Peel NFA (2008) . J Clin Endocrinol Metab, 93(4), 1317-1323.
Bowles SD, Jacques R, Hill TR, Eastell R & Walsh JS () . Nutrients, 16(17), 2888-2888.
Perri G, Mathers JC, Martin-Ruiz C, Parker C, Walsh JS, Eastell R, Demircan K, Chillon TS, Schomburg L, Robinson L & Hill TR () . British Journal of Nutrition, 1-10.
Perri G, Hill TR, Mathers JC, Walsh JS, Gossiel F, Winther K, Frölich J, Folkestad L, Cold S & Eastell R () . Journal of Bone and Mineral Research.
Paskins Z, Babatunde O, Sturrock A, Toh LS, Horne R, Maidment I, McCloskey E, Paskins Z, Armstrong D, Curtis E , Edwards J et al () . Osteoporosis International.
Orlando G, Bubbear J, Clarke S, Keen R, Roy M, Anilkumar A, Schini M, Walsh JS, Javaid MK & Ireland A () . Osteoporosis International.
Gossiel F, Ugur A, Peel NFA, Walsh JS & Eastell R () . Osteoporosis International.
Dowling L, McCloskey E, Cuthbertson DJ & Walsh JS () . The Journal of Frailty & Aging.
Durkin A, DeVile C, Arundel P, Bull M, Walsh J, Bishop NJ, Hupin E, Parekh S, Nadarajah R, Offiah AC , Calder A et al () . Journal of Medical Genetics.
Schini M, Hannan FM, Walsh JS & Eastell R () . Clinical Endocrinology.
Greenfield D, Blewitt A, Coleman R, Walsh J, Snowden J, Ross R & Han T () . Endocrine Abstracts.
Gossiel F, Naylor K, McCloskey E, Peel N, Walsh J, Paggiosi M & Eastell R () . Bone Abstracts.
Gossiel F, Hoyle C, McCloskey E, Walsh J, Peel N & Eastell R () . Bone Abstracts.
Naylor K, Paggiosi M, Gossiel F, McCloskey E, Peel N, Walsh J & Eastell R () . Bone Abstracts.

Chapters

Hossain M, Pezaro C, Walsh J, Rathbone E & Brown J (2019) Metabolic complications In Young A, Board R, Leonard P, Cooksley T, Stewart A & Michie C (Ed.), Problem solving in acute oncology (pp. 84-88). ebn Health
Rathbone E, Brown J & Walsh J (2013) Metabolic Complications In Marshall E, Clark P, Selby P & Young A (Ed.), Problem Solving in Acute Oncology Clinical Publishing

Conference proceedings papers

Moss KE, Keen R, Fang S, Zygouras A, Javaid M, Geberhiwot T, Poole K, Selby P, Walsh JS & Bubbear JS (2023) Mobility and Health-related Quality of Life in Adults with Pediatric-onset Hypophosphatasia Treated With Asfotase Alfa: Interim Analysis From the UK Managed Access Agreement. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 38 (pp 12-12)
Perri G, Hill T, Mathers JC, Walsh J, Gossiel F, Winther K, Frölich J, Folkestad L, Cold S & Eastell R (2021) . Proceedings of the Nutrition Society, Vol. 80(OCE3)
Perri G, Hill T, Mathers J, Mendonça N, Duncan R, Walsh J & Eastell R (2020) . Proceedings of the Nutrition Society, Vol. 79(OCE2)
Brown JE, Handforth C, Walsh J, Pezaro C, Sydes MR, Clarke NW, James ND & McCloskey E (2019) . Annals of Oncology, Vol. 30(Suppl 5) (pp v334-v335). Barcelona, Spain, 27 September 2019 - 1 October 2019.
Walsh JS, Evans AL, Naylor KE, Gossiel F, Bowles S, Jacques R & Eastell R (2014) LOW CIRCULATING 25 HYDROXYVITAMIN D IN OBESITY IS NOT ASSOCIATED WITH LOWER 24-HOUR URINE CALCIUM, HIGHER BONE TURNOVER OR LOWER BONE MINERAL DENSITY. OSTEOPOROSIS INTERNATIONAL, Vol. 25 (pp S672-S673)
Walsh⁎ JS, Newell-Price JD, Debono M & Eastell R (2012) . Bone, Vol. 50 (pp S53-S53)
Walsh JS, Henry YM, Fatayerji D & Eastell R (2006) Peak bone mineral content and bone volume at the lumbar spine in males and females: Longitudinal study.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S206-S207)
Walsh JS, Henry YM, Fatayerji D & Eastell R (2006) Endocrine determinants of bone turnover in adolescence and young adulthood.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S206-S206)
Walsh JS, Eastell R & Peel NF (2005) Effect of depot medroxyprogesterone acetate on markers of bone turnover.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 20(9) (pp S226-S226)
Walsh JS, Eastell R & Peel NF (2005) Effect of depot medroxyprogesterone acetate on attainment of peak bone mass. BONE, Vol. 36 (pp S129-S129)
Walsh JS, Clowes JA, Peel NF & Eastell R (2004) Bone size at the distal radius is inversely correlated with volumetric bone mineral density. OSTEOPOROSIS INTERNATIONAL, Vol. 15 (pp S26-S26)
Walsh JS, Clowes JA, Peel NF & Eastell R (2004) Bone size at the distal radius is inversely correlated with volumetric bone mineral density.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 19 (pp S301-S301)
Walsh JS, Eastell R & Peel NF (2003) Effect of depot medroxyprogesterone acetate on bone mineral density at the spine, hip and forearm.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 18 (pp S369-S369)
Gossiel F, McCloskey E, Walsh J, Naylor K, Peel N & Eastell R () . Bone Abstracts
Walsh JS, Evans AL, Bowles S, Naylor KE, Gossiel F, Jacques R, Schoenmakers I, Jones KS & Eastell R () . Bone Abstracts

Preprints

Mickute G, Staley K, Delaney H, Gardiner O, Hunter A, Keen R, Lockhart L, Meade N, Newman M, Ralston S , Rush E et al () , Research Square Platform LLC.

Research group

PhD students

Lisa Dowling

Teaching interests

I teach in the 91ֱ�� undergraduate curriculum, giving lectures and seminars on calcium physiology and metabolic bone disease, and masterclasses in teenage and young adult medicine. I run the AUBM training programme.

I lead the CIMA MRes in musculoskeletal ageing, and teach regularly on the ECTS PhD training course and Mellanby courses on bone biochemical markers and vertebral fracture.

I completed the RCP/UCL Postgraduate Diploma in Medical Education in 2012 and have since joined the RCP teaching team, as a tutor on the Doctors as Educators programme.
I am Training Programme Director for Endocrinology and Diabetes in South Yorkshire.

Professional activities and memberships

91ֱ�� Children’s Hospital Charity Scientific Advisory Committee 2014-
Brittle Bone Society Medical Board member 2012-
Member of Society for Endocrinology Special Interest groups:
Bone and Mineral, Late Effects of Cancer, Teenage and Young Adult 2010-
Organising and scientific programme committee for national Late Effects meetings 2012, 2014
Efficacy and Mechanism Evaluation associate board member 2011-2013