Elder, Charlotte, Dr

Dr Charlotte Elder

BSc, MBBS, PhD, DRCOG, MRCPCH

Clinical Medicine, School of Medicine and Population Health

Senior Clinical Lecturer in Paediatric Endocrinology

c.j.elder@sheffield.ac.uk

Room 10, The Damer Street Building, 91ֱ�� Children's Hospital

Full contact details

Dr Charlotte Elder
Clinical Medicine, School of Medicine and Population Health
Room 10, The Damer Street Building
91ֱ�� Children's Hospital
Western Bank
91ֱ��
S10 2TH

Profile

For enquiries, please contact – SMPH-West-Operational@sheffield.ac.uk

Charlotte Elder received her undergraduate medical degree from Imperial College, (University of London) UK in 1999 and after early training in London moved to 91ֱ�� in 2005 in pursuit of excellent paediatric endocrinology training and fabulous local countryside.

Dr Elder started working for the University of 91ֱ�� in 2009 when she undertook a Clinical Research Fellowship to study for her PhD. In 2011 she moved to a Clinical Lectureship, combining her PhD work with running the Child Health undergraduate course for The Medical School. Her PhD was awarded in 2015 and she returned to clinical medicine to train in tertiary level paediatric endocrinology and diabetes as an NIHR Academic Clinical Lecturer. In 2018 Dr Elder took up the post of Consultant in Paediatric Endocrinology and Diabetes at 91ֱ�� Children’s Hospital and was appointed as Senior Clinical Lecturer at the University. From 2021-2024 Dr Elder was a UKRI Biomedical Science Innovation Scholar. Clinically her specialist interests are adrenal insufficiency, adrenal function testing and paediatric and adolescent gynaecology.

Dr Elder is passionate about fostering research interests in junior colleagues and making research accessible for all health care professionals. She has supervised over 75 medical students and junior doctors, helping them present, publish and win prizes. Her enthusiasm extends to teaching and she was awarded a Clinical Teaching Award by the University in 2015. Charlotte leads the Paediatric Endocrinology module on the University’s Clinical Endocrinology & Diabetes MSc. She was Director of Undergraduate Medical Education at 91ֱ�� Children’s NHS Foundation Trust until 2024 and is currently a Fitness to Practice Investigator for the Medical School.

Research interests

Charlotte Elder's main research area is adrenal insufficiency, with the development of improved and non-invasive ways to test adrenal function, for which she has been awarded over £1.5m. She leads a team developing a non-invasive Short Synacthen Test (diagnostic test), using a novel formulation of Synacthen (Nasacthin) for nasal administration and the measurement of the glucocorticoid response in saliva samples. Nasacthin has patent applications filed or awarded in multiple global territories. Dr Elder is co-leading work to develop Waking Salivary Cortisone as a first line test for adrenal insufficiency. As part of this work her group has developed novel approaches to salivary collection in very young children, which won an NHS Innovation award, and are being used to understand more about adrenal function in preterm infants. In recognition of her work she was the winner of the Excellence in Research & Innovation award for 91ֱ�� Children’s NHS Foundation Trust in 2023.

Current projects:

Nasal Tetracosactide and Chitosan for Adrenal Stimulation - Chief Investigator on £1.2m MRC DPFS award to deliver
- Randomised, double-blinded, placebo-controlled cross-over trial in healthy women, men and children
- Randomised cross-over trial in a patient population with adrenal insufficiency
- Normative data study in healthy children to derive reference centiles for The Nasacthin Test (£156k UKRI Innovation Scholarship)
Neonatal adrenal function studies - lead
Steroid weaning studies - co-lead

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Dixon S, Lewis J, Debono M, Elder CJ, Caunt S, Jacques RM, Newell-Price J, Whitaker MJ, Keevil B & Ross RJ (2024) The cost-effectiveness of using waking salivary cortisol in the diagnosis of adrenal sufficiency. HEDS Discussion Paper Series(24.04).
Arshad MF, Elder C, Newell-Price J, Ross R & Debono M (2024) . The Journal of Clinical Endocrinology & Metabolism, 109(11), e2031-e2037.
Debono M, Caunt S, Elder C, Fearnside J, Lewis J, Keevil B, Dixon S & Ross R (2023) . Clinical Endocrinology, 99(6), 517-524.
Lawrence NR, Arshad MF, Pofi R, Ashby S, Dawson J, Tomlinson JW, Newell-Price J, Ross RJ, Elder CJ & Debono M (2023) . Journal of the Endocrine Society, 7(12).
Mushtaq T, Ali SR, Boulos N, Boyle R, Cheetham T, Davies JH, Elder CJ, Gan H-W, Hindmarsh PC, Katugampola H , Krone N et al (2023) . Archives of Disease in Childhood, 108(11), 871-878.
Debono M, Elder CJ, Lewis J, Fearnside J, Caunt S, Dixon S, Jacques RM, Newell-Price J, Whitaker MJ, Keevil B & Ross RJ (2023) . NEJM Evidence, 2(2).
Tonge JJ, Keevil BG, Craig JN, Whitaker MJ, Ross RJ & Elder CJ (2022) . Journal of Clinical Endocrinology and Metabolism, 107(11), 3128-3136.
Elder C, Vilela R, Johnson T, Taylor R, Kemp E, Keevil B, Cross A, Ross R & Wright N (2020) . Journal of Clinical Endocrinology and Metabolism, 105(8), 2692-2703.
Elder CJ, Langley J, Stanton A, De Silva S, Akbarian-Tefaghi L, Wales JKH & Wright NP (2019) . Clinical Endocrinology, 90(4), 623-629.
Elder CJ, Harrison RF, Cross AS, Vilela R, Keevil BG, Wright NP & Ross RJ (2018) . Clinical Endocrinology, 88(6), 772-778.
Cross AS, Helen Kemp E, White A, Walker L, Meredith S, Sachdev P, Krone NP, Ross RJ, Wright NP & Elder CJ (2018) . Clinical Endocrinology, 88(5), 744-751.
Elder CJ & Bishop NJ (2014) . Lancet, 383(9929), 1665-1676.
Elder CJ, Sachdev P & Wright NP (2012) . Archives of Disease in Childhood, 97(10), 870-873.
Elder CJ, Sachdev P & Wright NP (2012) . Arch Dis Child, 97(10), 870-873.

All publications

Journal articles

Dixon S, Lewis J, Debono M, Elder CJ, Caunt S, Jacques RM, Newell-Price J, Whitaker MJ, Keevil B & Ross RJ (2024) The cost-effectiveness of using waking salivary cortisol in the diagnosis of adrenal sufficiency. HEDS Discussion Paper Series(24.04).
Arshad MF, Elder C, Newell-Price J, Ross R & Debono M (2024) . The Journal of Clinical Endocrinology & Metabolism, 109(11), e2031-e2037.
Debono M, Caunt S, Elder C, Fearnside J, Lewis J, Keevil B, Dixon S & Ross R (2023) . Clinical Endocrinology, 99(6), 517-524.
Lawrence NR, Arshad MF, Pofi R, Ashby S, Dawson J, Tomlinson JW, Newell-Price J, Ross RJ, Elder CJ & Debono M (2023) . Journal of the Endocrine Society, 7(12).
Lawrence NR, Keevil BG, Elder C, Fearnside J, Caunt S, Dixon S, Newell-Price JDC, Ross RJM & Debono M (2023) . Journal of the Endocrine Society, 7(Supplement_1), bvad114.351.
Mushtaq T, Ali SR, Boulos N, Boyle R, Cheetham T, Davies JH, Elder CJ, Gan H-W, Hindmarsh PC, Katugampola H , Krone N et al (2023) . Archives of Disease in Childhood, 108(11), 871-878.
Cross AS, Moustafa M & Elder CJ (2023) . Archives of disease in childhood - Education & practice edition.
Debono M, Elder CJ, Lewis J, Fearnside J, Caunt S, Dixon S, Jacques RM, Newell-Price J, Whitaker MJ, Keevil B & Ross RJ (2023) . NEJM Evidence, 2(2).
Tonge JJ, Keevil BG, Craig JN, Whitaker MJ, Ross RJ & Elder CJ (2022) . Journal of Clinical Endocrinology and Metabolism, 107(11), 3128-3136.
Low A, Parry-Okeden S, Ferguson EC, Wright N & Elder CJ (2022) . Archives of Disease in Childhood: Education & Practice, 107(3), 182-187.
Craig JN, Sharman MR, Fitzgerald CG, Wigg D, Williams BS, Wilkinson EE, Wright NP, Langley J & Elder CJ (2021) . Journal of Pediatric Endocrinology and Metabolism, 34(1), 65-70.
Elder C, Vilela R, Johnson T, Taylor R, Kemp E, Keevil B, Cross A, Ross R & Wright N (2020) . Journal of Clinical Endocrinology and Metabolism, 105(8), 2692-2703.
Devaraja J, Elder C & Scott A (2020) . Endocrinology, Diabetes & Metabolism Case Reports, 2020(1).
Ferguson EC, Stewart EK, Hannah C & Elder CJ (2019) . Archives of Disease in Childhood.
Lawrence N, Cheetham T & Elder C (2019) . Clinical Endocrinology.
Bacila I-A, Elder C & Krone N (2019) . Archives of Disease in Childhood.
Elder CJ, Langley J, Stanton A, De Silva S, Akbarian-Tefaghi L, Wales JKH & Wright NP (2019) . Clinical Endocrinology, 90(4), 623-629.
Elder CJ, Harrison RF, Cross AS, Vilela R, Keevil BG, Wright NP & Ross RJ (2018) . Clinical Endocrinology, 88(6), 772-778.
Cross AS, Helen Kemp E, White A, Walker L, Meredith S, Sachdev P, Krone NP, Ross RJ, Wright NP & Elder CJ (2018) . Clinical Endocrinology, 88(5), 744-751.
Cockill TG, Hewitt A, Heafey C, Wright NP & Elder CJ (2017) . Journal of Pediatric Endocrinology and Metabolism, 30(12).
King D, West N & Elder CJ (2017) . Archives of Disease in Childhood Education and Practice Edition, 102(2), 94-99.
Elder CJ & Dimitri PJ (2017) . ADC Education & Practice.
Calvert A, West N & Elder C (2016) . Archives of Disease in Childhood, 101(Suppl 1).
Elder CJ & Dimitri P (2015) . Archives of Disease in Childhood.education and Practice Edition, 100(5), 272-276.
Elder CJ & Wright NP (2014) . Developmental Medicine & Child Neurology, 56(10), 921-922.
Elder CJ & Bishop NJ (2014) . Lancet, 383(9929), 1665-1676.
Elder CJ, Somerset LM, Ram V, Wright NP, Wales JK & Dimitri PJ (2014) . Clin Endocrinol (Oxf), 80(6), 925.
Jackson C, Wernham EM, Elder CJ & Wright NP (2013) . Practical Diabetes, 30(1), 16-18.
(2012) . Archives of Disease in Childhood, 97(11), 1008-1008.
Elder C, Hinchliffe C & Wright N (2012) . Diabetic Medicine, 29(9), 1213-1214.
Elder CJ, Sachdev P & Wright NP (2012) . Archives of Disease in Childhood, 97(10), 870-873.
Elder CJ, Sachdev P & Wright NP (2012) . Arch Dis Child, 97(10), 870-873.
Elder C, Hinchliffe C & Wright N (2010) . Journal of Clinical Pathology, 63(7), 660-660.
Elder CJ & Natarajan A (2010) Mauriac Syndrome - A Modern Reality. J PEDIATR ENDOCR MET, 23(3), 311-313.
Elder CJ, Wright VJ & Wright NP (2009) . ARCH DIS CHILD, 94(12), 1000-1001.
Elder CJ, Ackerman B & Kingdon C (2008) Audit cycle of newborn observations on the postnatal wards.. Archives of Disease in Childhood - Fetal and Neonatal Edition, 93(6), f475.
Elder CJ, Ackerman B & Kingdon C (2008) Audit cycle of newborn observations on the postnatal wards. ARCH DIS CHILD-FETAL, 93(6), 1475-1475.
Elder CJ, Barton JS, Brook CGD, Preece MA, Dattani MT & Hindmarsh PC (2008) . Hormone Research, 70(2), 89-92.
Pilling EL, Elder CJ & Gibson AT (2008) . Best Pract Res Clin Endocrinol Metab, 22(3), 447-462.
Elder CJ, Sprigg A & Coombs RC (2008) . Arch Dis Child Fetal Neonatal Ed, 93(1), F23.
Elder CJ & Urquhart DS (2006) Limitations of empirical therapy for bacterial meningitis in a healthy child with Listeria monocytogenes meningitis. Journal of Pediatric Neurology, 4(1), 65-67.
Tavernier M, Ross C, Jessica C, Balagamage C, Keevil B, Ross R, Debono M & Elder C () . Endocrine Abstracts.
Fahad AM, Lawrence N, Elder C, Newell-Price J, Ross R & Debono M () . Endocrine Abstracts.
Fahad AM, Elder C, Newell-Price J, Ross R & Debono M () . Endocrine Abstracts.
Mushtaq T, Ali S, Boulos N, Boyle R, Cheetham T, Davies J, Elder C, Gan H-W, Hindmarsh P, Katugampola H , Kerr S et al () . Endocrine Abstracts.

Conference proceedings papers

Burn S, Colyer S, Dimitri P, Wright N, Krone N & Elder C (2018) . Endocrine Abstracts, Vol. 90(S1) (pp 146-146), 27 September 2018 - 29 September 2018.
Aji A, Colyer S, Burn S, Dimitri P, Wright N, Krone N & Elder C (2018) . Hormone Research in Paediatrics, Vol. 90(Suppl 1) (pp 128-129), 27 September 2018 - 29 September 2018.
Cross AS, Sachdev P, Wright NP, Jabbar I & Elder CJ (2017) . British Society for Paediatric Endocrinology and Diabetes and British Society of Paediatric Gastroenterology, Hepatology and Nutrition
Aji A, Colyer S, Burn S, Dimitri P, Wright N, Krone N & Elder C () . Endocrine Abstracts

Research group

Lydia Foriestier-Zhang, MD Student