Franklin, Matthew, Dr

Dr Matthew Franklin

BA, MSc, PhD

Population Health, School of Medicine and Population Health

Senior Research Fellow

matt.franklin@sheffield.ac.uk
+44 114 222 4226

+44 114 222 0749

Regent Court (ScHARR)

Full contact details

Dr Matthew Franklin
Population Health, School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
91ֱ��
S1 4DA

Profile

I completed my BA in Economics and MSc in Economics and Health Economics at the University of 91ֱ�� in 2007 and 2008, respectively. I then moved to the University of Nottingham in 2008, working as a Health Economist Research Associate, as well as starting my PhD in Health Economics in 2010. I completed and passed my Viva for my PhD thesis, titled "The role of utility, health, and capabilities in economic evaluation: a case study in frail older people", as of December 2014.

My research has broadly focussed on estimating the comparative cost-effectiveness of different health and social care interventions using economic evaluation methods both within-study and for modelling-based analyses. I am particularly interested in the conduct of economic evaluations that use real-world data to support trials and observational studies. I have a keen interest in the philosophies of data science tasks, such as working out what we want to estimate, why, and to inform whom, and then working through if this is a description, prediction, or causal inference task. By understanding these philosophies, we can better work through the appropriate methods for the task at hand. I am particularly interested in tasks when causal inference is of interest, which is often the key interest in economic evaluation.

Research interests

I have a keen interest in the components of economic evaluation related to outcomes (particularly preference-based outcomes), resource use and costs. I have explored both the conceptual underpinning of relevant outcomes for economic evaluation (such as the focus on health and utilities, alongside other perspectives such as the capability approach), the estimation of these outcomes (such as appropriately estimating health utility, health state utilities, and quality-adjusted life years [QALYs]), and the psychometric properties of patient-reported outcomes with a focus on construct validity and responsiveness.

I have explored the use of both self-reported and electronic methods for capturing resource use, with a keen interest in the use of real-world data such as from administrative databases and electronic health records. I am also interested in how such real-world data can be used for costing studies, such as understanding the economic burden of health conditions and the affordability of current health and social care systems. I have used such considerations to explore what is a relevant and appropriate economic evidence-based to inform local compared to national decision-makers, for medical compared to public health considerations, in the context of service evaluations compared to research studies, and when considering average effects compared to the potential inequalities and inequities of such effects.

Economic evaluation and causal inference have a broad range of philosophies, methods, and uses, and I’m generally interested in exploring the nuances and complexities of each of these aspects. I have worked across a range of conditions and population groups, but I have a keen interest in mental health across the lifespan.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Franklin M, Pollard D, Sah J, Rayner A, Sun Y, Dube F, Sutton A & Qin L (2024) . Advances in Therapy.
Hunter RM & Franklin M (2024) . PharmacoEconomics - Open.
Franklin M, Hinde S, Hunter RM, Richardson G & Whittaker W (2024) . Applied Health Economics and Health Policy.
Franklin M & Hernández Alava M (2023) . Quality of Life Research, 32(10), 2763-2778.
Franklin M, Angus C, Welte T & Joos G (2023) . Applied Health Economics and Health Policy, 21, 547-558.
Franklin M, Hunter RM, Enrique A, Palacios J & Richards D (2022) . Value in Health, 25(6), 1018-1029.
Franklin M, Enrique A, Palacios J & Richards D (2021) . Quality of Life Research, 30(9), 2633-2647.
Franklin M, Lomas J & Richardson G (2020) . PharmacoEconomics, 38(7), 665-681.
Franklin M & Hunter RM (2019) . Age and Ageing.
Franklin M, Mukuria C, Mulhern B, Tran I, Brazier J & Watson S (2019) . The Patient - Patient-Centered Outcomes Research, 12(4), 405-417.
Franklin M, Lomas J, Walker S & Young T (2019) . PharmacoEconomics, 37(5), 631-643.
Franklin M & Thorn J (2019) . BMC Medical Research Methodology, 19.
Franklin M, Payne K & Elliott RA (2018) . Medical Decision Making, 38(1), 79-94.
Franklin M, Davis S, Horspool M, Kua WS & Julious S (2017) . PharmacoEconomics, 35(5), 561-573.
Franklin M, Wailoo A, Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB & Thornhill MH (2016) . Circulation, 134(20), 1568-1578.
Franklin M, Berdunov V, Edmans J, Conroy S, Gladman J, Tanajewski L, Gkountouras G & Elliott RA (2014) . Age and Ageing, 43(5), 703-707.
Franklin M, Shupo F, Wayi-Wayi G, Zibelnik N, Jones E, Mason N, Brazier J & Mukherjee S () . Oncology and Therapy.

Chapters

Franklin M (2017) , Mental Health Economics (pp. 89-119). Springer International Publishing
Berdunov V & Franklin M (2017) , Mental Health Economics (pp. 121-153). Springer International Publishing

Reports

Franklin M, Stone T, Baxter S, Haywood A, Hinde S, Howdon D, Jones M, Sutton A, Clowes M, Mason S , Lomas J et al (2022)
Franklin M, Stone T, Baxter S, Haywood A, Hinde S, Howdon D, Jones M, Sutton A, Clowes M, Mason S , Lomas J et al (2022)

All publications

Journal articles

Franklin M, Pollard D, Sah J, Rayner A, Sun Y, Dube F, Sutton A & Qin L (2024) . Advances in Therapy.
Hunter RM & Franklin M (2024) . PharmacoEconomics - Open.
Franklin M, Hinde S, Hunter RM, Richardson G & Whittaker W (2024) . Applied Health Economics and Health Policy.
Porter A, Franklin M, De Vocht F, d'Apice K, Curtin E, Albers P & Kidger J (2024) . BMJ Open, 14(1), e077220-e077220.
Hock ES, Franklin M, Baxter S, Clowes M, Chilcott J & Gillespie D (2023) . NIHR Open Research, 3(28).
Jones MC, Stone T, Mason SM, Eames A & Franklin M (2023) . BMJ Open, 13(10).
Mukherjee S, Shupo F, Wayi-Wayi G, Zibelnik N, Jones E, Mason N, Franklin M & Brazier J (2023) . eClinicalMedicine, 64, 102192-102192.
Franklin M & Hernández Alava M (2023) . Quality of Life Research, 32(10), 2763-2778.
Curtin EL, d’Apice K, Porter A, Widnall E, Franklin M, de Vocht F & Kidger J (2023) . BMC Health Services Research, 23(1).
Franklin M, Angus C, Welte T & Joos G (2023) . Applied Health Economics and Health Policy, 21, 547-558.
Murphy LA, Akehurst R, Solà-Morales O, Cunningham D, Mestre-Ferrandiz J, Franklin M & de Pouvourville G (2023) . Value in Health.
Baxter S, Franklin M, Haywood A, Stone T, Jones M, Mason S & Sterniczuk K (2023) . BMC Public Health, 23(1).
Murphy LA, Akehurst R, Solà-Morales O, Cunningham D, Mestre-Ferrandiz J, Franklin M & de Pouvourville G (2023) . Value in Health.
Howdon D, Hinde S, Lomas J & Franklin M (2022) . Applied Health Economics and Health Policy, 20(6), 783-792.
Kwon J, Squires H, Franklin M & Young T (2022) . Cost Effectiveness and Resource Allocation, 20(1).
Hinde S, Howdon D, Lomas J & Franklin M (2022) . Applied Health Economics and Health Policy, 20(6), 793-802.
Mason S, Stone T, Jacques R, Lewis J, Simpson R, Kuczawski M & Franklin M (2022) . Medical Decision Making, 42(8), 999-1009.
Kwon J, Squires H, Franklin M, Lee Y & Young T (2022) . BMC Health Services Research, 22(1).
Kwon J, Squires H, Franklin M, Lee Y & Young T (2022) . BMC Health Services Research, 22(1).
Franklin M, Hunter RM, Enrique A, Palacios J & Richards D (2022) . Value in Health, 25(6), 1018-1029.
Franklin M & Young T (2021) . Evidence Based Mental Health, 24(4).
Franklin M, Enrique A, Palacios J & Richards D (2021) . Quality of Life Research, 30(9), 2633-2647.
Sousa S, Robinson L, Franklin M & Watson S (2020) . Journal of Affective Disorders, 276, 848-849.
Franklin M, Lomas J & Richardson G (2020) . PharmacoEconomics, 38(7), 665-681.
Richards D, Enrique A, Eilert N, Franklin M, Palacios J, Duffy D, Earley C, Chapman J, Jell G, Sollesse S & Timulak L (2020) . npj Digital Medicine, 3(1).
Franklin M & Hunter RM (2019) . Age and Ageing.
Crocker TF, Brown L, Clegg A, Farley K, Franklin M, Simpkins S & Young J (2019) . Quality of Life Research, 28(8), 2041-2056.
Franklin M, Mukuria C, Mulhern B, Tran I, Brazier J & Watson S (2019) . The Patient - Patient-Centered Outcomes Research, 12(4), 405-417.
Franklin M, Lomas J, Walker S & Young T (2019) . PharmacoEconomics, 37(5), 631-643.
Franklin M & Thorn J (2019) . BMC Medical Research Methodology, 19.
Julious SA, Horspool MJ, Davis S, Franklin M, Smithson WH, Norman P, Simpson RM, Elphick H, Bortolami O & Cooper C (2018) . BMJ Open, 8(4).
Richards D, Duffy D, Blackburn B, Earley C, Enrique A, Palacios J, Franklin M, Clarke G, Sollesse S, Connell S & Timulak L (2018) . BMC Psychiatry, 18.
Cox M, O’Connor C, Biggs K, Hind D, Bortolami O, Franklin M, Collins B, Walters S, Wailoo A, Channell J , Albert P et al (2018) . Health Technology Assessment, 22(11), 1-204.
Franklin M, Payne K & Elliott RA (2018) . Medical Decision Making, 38(1), 79-94.
Franklin M, Davis S, Horspool M, Kua WS & Julious S (2017) . PharmacoEconomics, 35(5), 561-573.
Julious SA, Horspool MJ, Davis S, Bradburn M, Norman P, Shephard N, Cooper CL, Smithson WH, Boote J, Elphick H , Loban A et al (2016) . Health Technology Assessment, 20(93), 1-154.
Franklin M, Wailoo A, Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB & Thornhill MH (2016) . Circulation, 134(20), 1568-1578.
Tanajewski L, Franklin M, Gkountouras G, Berdunov V, Harwood RH, Goldberg SE, Bradshaw LE, Gladman JRF & Elliott RA (2015) . PLOS ONE, 10(12), e0140662-e0140662.
Tanajewski L, Franklin M, Gkountouras G, Berdunov V, Edmans J, Conroy S, Bradshaw LE, Gladman JRF & Elliott RA (2015) . PloS one, 10(5), e0121340.
Gladman J, Harwood R, Conroy S, Logan P, Elliott R, Jones R, Lewis S, Dyas J, Schneider J, Porock D , Pollock K et al (2015) . Programme Grants for Applied Research, 3(4), 1-410.
Franklin M, Berdunov V, Edmans J, Conroy S, Gladman J, Tanajewski L, Gkountouras G & Elliott RA (2014) . Age and Ageing, 43(5), 703-707.
Elliott RA, Putman KD, Franklin M, Annemans L, Verhaeghe N, Eden M, Hayre J, Rodgers S, Sheikh A & Avery AJ (2014) . PharmacoEconomics, 32(6), 573-590.
Gordon AL, Franklin M, Bradshaw L, Logan P, Elliott R & Gladman JRF (2014) . Age and Ageing, 43(1), 97-103.
Edmans J, Bradshaw L, Franklin M, Gladman J & Conroy S (2013) . BMJ, 347(oct08 2), f5874-f5874.
Edmans J, Bradshaw L, Gladman JRF, Franklin M, Berdunov V, Elliott R & Conroy SP (2013) . Age and Ageing, 42(6), 747-753.
Wou F, Gladman JRF, Bradshaw L, Franklin M, Edmans J & Conroy SP (2013) . Age and Ageing, 42(6), 776-781.
Morriss R, Kai J, Atha C, Avery A, Bayes S, Franklin M, George T, James M, Malins S, McDonald R , Patel S et al (2012) . BMC Family Practice, 13(1).
Avery AJ, Rodgers S, Cantrill JA, Armstrong S, Cresswell K, Eden M, Elliott RA, Howard R, Kendrick D, Morris CJ , Prescott RJ et al (2012) . The Lancet, 379(9823), 1310-1319.
Edmans J, Conroy S, Harwood R, Lewis S, Elliott RA, Logan P, Bradshaw L, Franklin M & Gladman J (2011) . Trials, 12(1).
Franklin M, Shupo F, Wayi-Wayi G, Zibelnik N, Jones E, Mason N, Brazier J & Mukherjee S () . Oncology and Therapy.
Mukuria C, Franklin M & Hinde S () . The European Journal of Health Economics.

Chapters

Franklin M (2017) , Mental Health Economics (pp. 89-119). Springer International Publishing
Berdunov V & Franklin M (2017) , Mental Health Economics (pp. 121-153). Springer International Publishing

Conference proceedings papers

Franklin M, Porter A, de Vocht F, Kearns B, Latimer N, Hernandez M, Young T & Kidger J (2023) COMBINING CAUSAL INFERENCE AND WITHIN-TRIAL ECONOMIC EVALUATION METHODS TO ASSESS THE COST-EFFECTIVENESS OF A MENTAL HEALTH SERVICE USING REAL-WORLD DATA: THE QUASI-EXPERIMENTAL ADAPT STUDY. VALUE IN HEALTH, Vol. 26(12) (pp S87-S87)
Mukherjee S, Franklin M, Shupo F, Mason N, Wayi-Wayi G, Zibelnik N, Repasky M & Brazier J (2022) . Blood, Vol. 140(Supplement 1) (pp 10885-10886)
Franklin M, Jones E, Shupo F, Mason N, Wayi-Wayi G, Zibelnik N, Repasky M, Mukherjee S & Brazier JE (2022) SYMPTOM BURDEN AND ITS IMPACT ON DAILY LIVING WITH IDIOPATHIC MULTICENTRIC CASTLEMANS DISEASE: DEVELOPMENT AND PSYCHOMETRIC VALIDATION OF A BESPOKE INTERNATIONAL PATIENT AND CAREGIVER SURVEY. VALUE IN HEALTH, Vol. 25(12) (pp S416-S417)
Franklin M & Thorn J (2017) Self-reported and electronic resource use for trial-based economic evaluations: the current state of play in England and considerations for the future. TRIALS, Vol. 18
Elphick H, Horspool M, Davis S, Bradburn M, Norman P, Shephard N, Cooper C, Smithson WH, Boote J, Loban A , Franklin M et al (2016) . 1.6 General Practice and Primary Care
Franklin M, Tran I, Stoneman D & Watson S (2016) . Value in Health, Vol. 19(7) (pp A608-A608)
Berdunov V, Franklin M, Tanajewski L, Harwood R, Goldberg S, Gladman J & Elliott RA (2013) . Value in Health, Vol. 16(7) (pp A335-A335)
Franklin M, Gkountouras G, Berdunov V, Tanajewski L, Gladman J & Elliott RA (2013) . Value in Health, Vol. 16(7) (pp A578-A578)
Elliott RA, Putman K, Franklin M, Verhaeghe N, Annemans L, Eden M, Hayre J & Avery A (2013) . Value in Health, Vol. 16(3) (pp A206-A206)
Elliott RA, Franklin M, Berdunov V, Gkountouras G, Edmans J, Conroy S, Bradshaw L, Tanajewski L & Gladman J (2013) . Value in Health, Vol. 16(3) (pp A20-A20)
Franklin M, Elliott RA, Payne K, Conroy S, Edmans J, Goldberg S, Gordon A, Harwood R & Gladman J (2013) . Value in Health, Vol. 16(3) (pp A196-A196)

Reports

Franklin M, Stone T, Baxter S, Haywood A, Hinde S, Howdon D, Jones M, Sutton A, Clowes M, Mason S , Lomas J et al (2022)
Baxter S, Franklin M & Sterniczuk K (2022)
Franklin M, Stone T, Baxter S, Haywood A, Hinde S, Howdon D, Jones M, Sutton A, Clowes M, Mason S , Lomas J et al (2022)
Ariss S, Read J, Franklin M, Dawson J, Nasr N, Scott E, Field R, Lowrie K, Cook L & Simmonds R (2018) 91ֱ�� City Region Test Bed, ‘Perfect Patient Pathway’ final evaluation report
Keetharuth D, Mulhern B, Wong R, Ara R, Franklin M, Jones G & Brazier JE (2015) Supporting the routine collection of patient reported outcome measures in the National Clinical Audit Work Package 2. How should PROMS data be collected?

Datasets

Clowes M, Sutton A, Stone T & Franklin M (2022) .

Presentations

Franklin M, Shupo F, Jones E, Mason N, Wayi-Wayi G, Kanhai K, Zibelnick N, Repasky M, Makarounas-Kirchmann K, Mukherjee S & Brazier J .
Franklin M, Shupo F, Jones E, Mason N, Wayi-Wayi G, Kanhai K, Zibelnick N, Repasky M, Makarounas-Kirchmann K, Mukherjee S & Brazier J PB2708: SYMPTOM BURDEN AND ITS IMPACT ON DAILY LIFE IN PATIENTS WITH IDIOPATHIC MULTICENTRIC CASTLEMAN’S DISEASE (IMCD): AN EXPLORATORY ANALYSIS OF THE SURVEY’S INTERNAL CONSTRUCT VALIDITY.

Other

Richards D, Enrique A, Eilert N, Franklin M, Palacios J, Duffy D, Earley C, Chapman J, Jell G, Sollesse S & Timulak L (2020) . NPJ Digit Med, 3(1), 91-91.

Preprints

Cherodian R, Franklin M, Baxter S, Chilcott J & Gillespie D (2024) , Cold Spring Harbor Laboratory.
Hock ES, Franklin M, Baxter S, Clowes M, Chilcott J & Gillespie D (2023) .
Hock ES, Franklin M, Baxter S, Clowes M, Chilcott J & Gillespie D (2023) , Cold Spring Harbor Laboratory.
Curtin EL, d'Apice K, Porter A, Widnall E, Franklin M, de Vocht F & Kidger J (2022) , Research Square Platform LLC.
Kwon J, Squires H, Franklin M, Lee MY & Young T (2021) , Research Square Platform LLC.
Kwon J, Squires H, Franklin M, Lee Y & Young T (2021) , Research Square Platform LLC.
Kwon J, Lee Y, Squires H, Franklin M & Young T (2021) , Research Square Platform LLC.

Teaching activities

Course Deputy Director for MSc Health Economics and Decision Modelling (HEDM)

Health Economics and Decision Modelling MSc

Postgraduate taught

September 2025 start
1 year 2 years 3 years Full-time Part-time

Develop the theoretical and analytical skills you need for a career in the growing field of health economics. Learn how to model, analyse and evaluate healthcare interventions so you can make informed public health decisions.

Professional activities and memberships

Health Economics and Decision Science (HEDS) section lead for Knowledge Exchange (KE)

Member of the

co-lead for Real-World Evidence for Health Technology Assessment